Science

Metastatic colorectal cancer (mCRC) refers to colorectal cancer that has spread beyond the colon or rectum to other parts of the body, such as the liver, lungs, or lymph nodes. Here are some key aspects of mCRC. According to the American Cancer Society (2024 estimates) 153,020 new cases of colorectal cancer will be diagnosed in the US. About 25% (38,000) will be diagnosed at the metastatic stage. mCRC is responsible for most colorectal cancer-related deaths. Treatment options include chemotherapy, targeted therapies, immunotherapy, surgery, and radiation therapy. The median survival for untreated mCRC is approximately 6-9 months and with treatment, median survival can range from 24-30 months or more, depending on the treatment regimen and individual patient factors.